| Bioactivity | hUP1-IN-1 is a hUP1 inhibitor with Kii and Kis Urd of 375 and 635 nM. hUP1-IN-1 showes inhibitory activities over hUP1 catalyzed reaction with 70% at 1 μM. hUP1-IN-1 can be used for the research of cancer.[1] |
| Name | hUP1-IN-1 |
| CAS | 5444-02-0 |
| Formula | C7H6N2O2 |
| Molar Mass | 150.13 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Renck D, et al. Design of novel potent inhibitors of human uridine phosphorylase-1: synthesis, inhibition studies, thermodynamics, and in vitro influence on 5-fluorouracil cytotoxicity. J Med Chem. 2013 Nov 14;56(21):8892-902. |