| Bioactivity | hPL-IN-2 (compound 2u) is a potent, reversible, and non-competitive inhibitor of pancreatic lipase (IC50: 1.63 μM) and can be used in anti-obesity research[1]. |
| Target | IC50: 1.63 μM (Pancreatic lipase, PL); Ki：1.7 μM (human PL) |
| Name | hPL-IN-2 |
| CAS | 24900-61-6 |
| Formula | C19H11Cl4NO3 |
| Molar Mass | 443.11 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zhao Y, et al. Design, synthesis and biological evaluation of salicylanilides as novel allosteric inhibitors of human pancreatic lipase. Bioorg Med Chem. 2023 Aug 15;91:117413.. |