| Bioactivity | hNTS1R agonist-1 (Compound 10) is a BBB permeable hNTS1R full agonist (Ki: 6.9 nM) . hNTS1R agonist-1 increases motor function and memory in a mouse model of Parkinson's disease (PD). hNTS1R agonist-1 is a Neurotensin(8-13) analog and is a neuroprotective agent[1]. |
| Name | hNTS1R agonist-1 |
| Sequence | Lys-{Cav}-Pro-Tyr-Ile-Leu |
| Shortening | K-{Cav}-PYIL |
| Formula | C37H62N10O9 |
| Molar Mass | 790.95 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Kühl T, et al. Neurotensin(8-13) analogs as dual NTS1 and NTS2 receptor ligands with enhanced effects on a mouse model of Parkinson's disease. Eur J Med Chem. 2023 Jun 5;254:115386. |
hNTS1R agonist-1
CAS: F: C37H62N10O9 W: 790.95
hNTS1R agonist-1 (Compound 10) is a BBB permeable hNTS1R full agonist (Ki: 6.9 nM) . hNTS1R agonist-1 increases motor fu
Data collection：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.