hCAIX/XII-IN-4_product_DataBase

CAS: 1119200-33-7 F: C20H16N2O5 W: 364.35

hCAIX/XII-IN-4 (compound 6c) is a potent CAIX/XII inhibitor with the Ki values of 4.5 nM, 23.6 nM, >10000 nM and >10000

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity	hCAIX/XII-IN-4 (compound 6c) is a potent CAIX/XII inhibitor with the Ki values of 4.5 nM, 23.6 nM, >10000 nM and >10000 nM for CAXII, CAIX, CAI and CAⅡ, respectively[1].
Target	Ki: 4.5 nM (CAXII), 4.5 nM (CAXII), >10000 nM (CAI), and > 10000 nM (CAⅡ)
Name	hCAIX/XII-IN-4
CAS	1119200-33-7
Formula	C20H16N2O5
Molar Mass	364.35
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Thacker PS, et, al. Design, synthesis and biological evaluation of coumarin linked 1,2,4-oxadiazoles as selective carbonic anhydrase IX and XII inhibitors. Bioorg Chem. 2020 May;98:103739.

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