| Bioactivity | hCAIX/XII-IN-11 (Compound 6c) is an inhibitor of hCA IX and hCA XII with a Ki value of 0.7 μM for both the isoforms. hCAIX/XII-IN-11 can be used for anticancer research[1]. |
| Invitro | hCAIX/XII-IN-11 shows cytotoxic activity against A549 lung cancer cells, with IC50 value of 81 μM[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> hCAIX/XII-IN-11 相关抗体: |
| Formula | C13H10FN3O4 |
| Molar Mass | 291.23 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Siwach K, et al. 1,2,3-Triazole-based esters and carboxylic acids as nonclassical carbonic anhydrase inhibitors capable of cathepsin B inhibition. Arch Pharm (Weinheim). 2024 Mar;357(3):e2300372. |