| Bioactivity | hCAIX/VII-IN-1 is a selective hCA VII/IX inhibitor. hCAIX/VII-IN-1 inhibit hCAⅠ, hCAⅡ, hCAⅣ, hCAⅦ and hCAⅨ with Ki values of 336.2 nM,185.8 nM, 1055 nM, 35.6 nM and 28.0 nM, respectively. hCAIX/VII-IN-1 can be used for the research of cancer and neurological diseases[1]. |
| Target | Ki: hCAⅠ(336.2 nM), hCAⅡ(185.8 nM), hCAⅣ(1055 nM), hCAⅦ(35.6 nM), hCAⅨ(28.0 nM). |
| Name | hCAIX/VII-IN-1 |
| Formula | C16H13BFN3O3 |
| Molar Mass | 325.10 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Nocentini A, et al. 6-Substituted Triazolyl Benzoxaboroles as Selective Carbonic Anhydrase Inhibitors: In Silico Design, Synthesis, and X-ray Crystallography. J Med Chem. 2023 Jun 22;66(12):8118-8129. |