| Bioactivity | hCAIX-IN-19 is a sulfonamides inhibitor against hCA IX with an inhibition constant (KI ) of 6.2 nM and show good selectivity over hCA I (hCA I/ hCA IX = 117)[1]. |
| Invitro | hCAIX-IN-19 (1.0-100.0 μM, 48h)在 U87MG 细胞、MDA-MB-231 细胞和 PANC-1 细胞中显示出抗增殖活性[1]。 0 --> hCAIX-IN-19 相关抗体: Cell Proliferation Assay[1] Cell Line: |
| Name | hCAIX-IN-19 |
| Formula | C29H34N4O4S2 |
| Molar Mass | 566.73 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Begines P, et al. Design and synthesis of sulfonamides incorporating a biotin moiety: Carbonic anhydrase inhibitory effects, antiproliferative activity and molecular modeling studies [J]. Bioorganic & Medicinal Chemistry, 2023, 94: 117467. |