hCAII-IN-9_product_DataBase

CAS: 2878477-18-8 F: C15H16ClN3O5S2 W: 417.89

hCAII-IN-9 is a potent carbonic anhydrase inhibitor with IC50s of 1.18 μM (hCA II), 0.17 μM (hCA IX), and 2.99 μM (h

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity	hCAII-IN-9 is a potent carbonic anhydrase inhibitor with IC50s of 1.18 μM (hCA II), 0.17 μM (hCA IX), and 2.99 μM (hCA XII), respectively. hCAII-IN-9 has no blood-brain barrier permeability[1].
Invitro	hCAII-IN-9 (化合物 11) (100 μM; 24-48 h) 抑制BHK-21和HEK-293细胞，细胞存活率分别为48%和72%[1]。
In Vivo	hCAII-IN-9 (compound 11) 无血脑屏障通透性[1]。
Name	hCAII-IN-9
CAS	2878477-18-8
Formula	C15H16ClN3O5S2
Molar Mass	417.89
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Hussain Z, et al. Synthesis and Evaluation of Amide and Thiourea Derivatives as Carbonic Anhydrase (CA) Inhibitors. ACS Omega. 2022 Dec 6;7(50):47251-47264.

PeptideDB