Bioactivity | hAChE/hBuChE/GSK-3β-IN-1 (Compound 6c) is a BBB-penatrable and multi-target anti-Alzheimer's disease compound. hAChE/hBuChE/GSK-3β-IN-1 is the inhibitors of hAChE (IC50: 28.88 nM), hBuChE (IC50: 131.90 nM) and GSK-3β (IC50: 51.42 nM). hAChE/hBuChE/GSK-3β-IN-1 is the tau and Aβ protein aggregation inhibitors[1]. |
Formula | C19H15NO4 |
Molar Mass | 321.33 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Abd El-Mageed MMA, et al. Rational design, synthesis and computational studies of multi-targeted anti-Alzheimer's agents integrating coumarin scaffold. Bioorg Chem. 2025 Jan;154:108024. |