Bioactivity | h-NTPDase-IN-5 (compound 3b) is a pan-inhibitor of NTPDase with IC50s of 1.10 μM (h-NTPDase1), 44.73 μM (h-NTPDase2), 26.14 μM (h-NTPDase3), 0.32 μM (h- NTPDase8). |
Target | IC50: 1.10 μM (h-NTPDase1), 44.73 μM (h-NTPDase2), 26.14 μM (h-NTPDase3), 0.32 μM (h- NTPDase8) |
Name | h-NTPDase-IN-5 |
CAS | 2939932-93-9 |
Formula | C23H21N3O2S |
Molar Mass | 403.50 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Zaman G, Ullah S, Uzair M, et al. Synthesis of Thieno [3, 2‐d] pyrimidine Derivatives through Sequential SNAr and Suzuki Reactions as Selective h‐NTPDases Inhibitors[J]. ChemMedChem, 2023: e202300165. |