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ent-Kaurane-3α,16β,17-triol

CAS: 130855-22-0 F: C20H34O3 W: 322.48

ent-Kaurane-3α,16β,17-triol (Compound 3) is an anticancer agent. ent-Kaurane-3α,16β,17-triol induces apoptosis in HC
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Bioactivity ent-Kaurane-3α,16β,17-triol (Compound 3) is an anticancer agent. ent-Kaurane-3α,16β,17-triol induces apoptosis in HCT116 cells[1].
Invitro ent-Kaurane-3α,16β,17-triol (Compound 3; 0-100 μM; 24 h) 抑制 HepG2 和 HCT116 细胞增殖,IC50 值分别为 45.5 和 29.84 µM[1]。ent-Kaurane-3α,16β,17-triol (20 and 30 μM; 24 h) 抑制 HCT116 细胞集落形成[1]。ent-Kaurane-3α,16β,17-triol (30 and 40 µM; 48 h) 诱导人结肠癌细胞周期阻滞[1]。ent-Kaurane-3α,16β,17-triol (30 and 40 µM; 72 h) 诱导人结肠癌细胞凋亡[1]。 Cell Viability Assay[1] Cell Line:
Name ent-Kaurane-3α,16β,17-triol
CAS 130855-22-0
Formula C20H34O3
Molar Mass 322.48
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Chen X, et al. Identification of terpenoids from Rubus corchorifolius L. f. leaves and their anti-proliferative effects on human cancer cells. Food Funct. 2017 Mar 22;8(3):1052-1060.