| Bioactivity | eeAChE/eqBuChE-IN-1 (compound 3F) is a reversible dual eeAChE/eqBuChE inhibitor with IC50s of 1.3?μM and 0.81?μM, respectively. eeAChE/eqBuChE-IN-1 exhibits anti-inflammatory activity. eeAChE/eqBuChE-IN-1 also shows neuroprotective effect on Aβ25-35-induced PC12 cell injury[1]. |
| Target | IC50: 1.3?μM (eeAChE) and 0.81?μM (eqBuChE) |
| Name | eeAChE/eqBuChE-IN-1 |
| CAS | 2921654-26-2 |
| Formula | C14H16N2O2 |
| Molar Mass | 244.29 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Chen h, et, al. Design, synthesis and evaluation of quinoline- O-carbamate derivatives as multifunctional agents for the treatment of Alzheimer's disease. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2169682. |
eeAChE/eqBuChE-IN-1
CAS: 2921654-26-2 F: C14H16N2O2 W: 244.29
eeAChE/eqBuChE-IN-1 (compound 3F) is a reversible dual eeAChE/eqBuChE inhibitor with IC50s of 1.3?μM and 0.81?μM, resp
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