| Bioactivity | eIF4E-IN-6(compound 4b) is a GMP analogs synthesized to targeteIF4Eand restrain its binding to cap mRNA.eIF4E-IN-6shows cell cytotoxicity against Caco-2, HepG-2,and MCF-7 cells, withIC50values of 31, 27, and 21 μM, respectively[1]. |
| Target | 31, 27, and 21 μM(Caco-2, HepG-2,and MCF-7) |
| Name | eIF4E-IN-6 |
| Formula | C33H32BrN9NaO12P |
| Molar Mass | 880.53 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Attia RT, et al. Newly Synthesized Anticancer Purine Derivatives Inhibiting p-EIF4E Using Surface-Modified Lipid Nanovesicles. ACS Omega. 2023;8(41):37864-37881. Published 2023 Oct 6. |