| Bioactivity | dWIZ-1 is a potent WIZ molecular glue degrader. dWIZ-1 recruitments WIZ(ZF7) to cereblon (CRBN) induces WIZ degradation. dWIZ-1 has the potential for the research of sickle cell disease (SCD)[1]. |
| CAS | 2879251-63-3 |
| Formula | C22H29N3O4 |
| Molar Mass | 399.48 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ting PY, et al. A molecular glue degrader of the WIZ transcription factor for fetal hemoglobin induction. Science. 2024 Jul 5;385(6704):91-99. |