Bioactivity | dCE-2 is a PROTAC targeting CBP/EP300. dCE-2 consists of E3 ubiquitin ligase ligand Thalidomide-4-OH (HY-103596), PROTAC Linker tert-Butyl 11-aminoundecanoate (HY-130715) and PROTAC target protein ligand EP300/CBP ligand 2 (HY-161960), of which the target protein ligand activity control is EP300/CBP ligand 1 (HY-161959), and the conjugate of E3 ubiquitin ligase ligand + Linker is Thalidomide-NH-C10-Boc (HY-161961)[1]. |
Target | CBP/EP300 |
Formula | C44H47N9O6 |
Molar Mass | 797.90 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |