| Bioactivity | dBAZ2 is a first-in-class BAZ2A and BAZ2B PROTAC degrader with DC50 values of 180 nM and 250 nM for BAZ2A and BAZ2B, respectively. (Blue: E3 ligase ligand (VH 101, thiol (HY-47851); Black: linker (HY-168450); pink: target protein ligand (HY-168449))[1]. |
| Formula | C54H64FN11O5S2 |
| Molar Mass | 1030.29 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Leonardo Palaferri, et al. Discovery of First-in-Class BAZ2A/B and BAZ2B-Selective Degraders. ACS Med Chem Lett. January 7, 2025. |