| Bioactivity | dALK-3 is an anaplastic lymphoma kinase (ALK) degrader. dALK-3 can effectively induce EML4-ALK degradation with a DC50 of 0.182 μM. dALK-3 has good anti-proliferation activity against H3122 cells and can be used in the study of cancer[1]. |
| Formula | C39H45ClN7O5P |
| Molar Mass | 758.25 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Yu N, et al. Design and evaluation of anaplastic lymphoma kinase degraders using a covalent fumarate handle. Bioorg Med Chem Lett. 2024 Dec 15;117:130075. |