| Bioactivity | d-(KLAKLAK)2, as an antibacterial and anti-tumor polypeptide, is a representative of the antimicrobial peptide group, and also has good anticancer properties. d-(KLAKLAK)2 is able to kill bacteria by damaging their cell membranes, causing cell contents to leak out. d-(KLAKLAK)2 can also inhibit tumor cell proliferation by causing mitochondrial swelling and mitochondrial membrane destruction, triggering apoptosis (programmed cell death)[1]. |
| CAS | 721397-24-6 |
| Sequence | {d-(Lys-Leu-Ala-Lys-Leu-Ala-Lys-Lys-Leu-Ala-Lys-Leu-Ala-Lys)}-NH2 |
| Shortening | {d-(KLAKLAKKLAKLAK)}-NH2 |
| Formula | C72H139N21O14 |
| Molar Mass | 1523.01 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Jaber S, et al. Synthesis, antitumor and antibacterial studies of new shortened analogues of (KLAKLAK) 2-NH2 and their conjugates containing unnatural amino acids[J]. Molecules, 2021, 26(4): 898. |
d-(KLAKLAK)2, Proapoptotic Peptide
CAS: 721397-24-6 F: C72H139N21O14 W: 1523.01
d-(KLAKLAK)2, as an antibacterial and anti-tumor polypeptide, is a representative of the antimicrobial peptide group, an
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