| Bioactivity | cpm-1285m is a cell-permeable Bcl-2 inhibitory peptide. cpm-1285m enters HL-60 tumor cells, binds to Bcl-2 protein, and induces apoptosis in vitro. cpm-1285m can slow down tumor growth in mouse models and can be used in cancer research[1]. |
| Name | cpm-1285m |
| Sequence | {Decanoy}-Lys-Asn-Leu-Trp-Ala-Ala-Gln-Arg-Tyr-Gly-Arg-Glu-Ala-Arg-Arg-Met-Ser-Asp-Glu-Phe-Glu-Gly-Ser-Phe-Lys-Gly-Leu |
| Shortening | {Decanoy}-KNLWAAQRYGREARRMSDEFEGSFKGL |
| Formula | C150H234N44O42S |
| Molar Mass | 3357.80 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Wang JL, et al. Cell permeable Bcl-2 binding peptides: a chemical approach to apoptosis induction in tumor cells. Cancer Res. 2000 Mar 15;60(6):1498-502. |