closed-HMRG

CAS: 7449-51-6 F: C20H16N2O2 W: 316.35

closed-HMRG is HMRG with closed spirocyclic structure. Ac-HMRG, an acetylated derivative of hydroxymethyl rhodamine gree

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Bioactivity	closed-HMRG is HMRG with closed spirocyclic structure. Ac-HMRG, an acetylated derivative of hydroxymethyl rhodamine green, exists as a closed spirocyclic structure in aqueous solution at physiological pH, whereas HMRG itself takes an open nonspirocyclic structure. Ac-HMRG is colorless and nonfluorescent and HMRG is strongly fluorescent[1].
CAS	7449-51-6
Formula	C20H16N2O2
Molar Mass	316.35
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Masayo Sakabe, et al. Rational design of highly sensitive fluorescence probes for protease and glycosidase based on precisely controlled spirocyclization. J Am Chem Soc. 2013 Jan 9;135(1):409-14.