Bioactivity | cis-ent-Tadalafil (Tadalafil EP Impurity C) is a highly potent PDE5 inhibitor with an IC50 value of 5 nM and has blood pressure lowering activity[1]. | ||||||||||||
Name | cis-ent-Tadalafil | ||||||||||||
CAS | 171596-28-4 | ||||||||||||
Formula | C22H19N3O4 | ||||||||||||
Molar Mass | 389.40 | ||||||||||||
Appearance | Solid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. Daugan A, et al. The discovery of tadalafil: a novel and highly selective PDE5 inhibitor. 2: 2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione analogues. J Med Chem. 2003 Oct 9;46(21):4533-42. |