Bioactivity | cis-Tadalafil is a PDE5 inhibitor (IC50: 0.09 μM). cis-Tadalafil can be used for research of cardiovascular diseases[1]. |
Invitro | cis-Tadalafil (Compound 12b) 抑制 PDE5,IC50 为 0.09 μM[1]。 |
Name | cis-Tadalafil |
CAS | 171596-27-3 |
Formula | C22H19N3O4 |
Molar Mass | 389.40 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Daugan A, et al. The discovery of tadalafil: a novel and highly selective PDE5 inhibitor. 2: 2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione analogues. J Med Chem. 2003 Oct 9;46(21):4533-42. |