PeptideDB

cis-ACBD

CAS: 73550-55-7 F: C6H9NO4 W: 159.14

cis-ACBD is a potent and selective inhibitor of the high-affinity, Na+-dependent plasma membrane glutamate transporter.
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Bioactivity cis-ACBD is a potent and selective inhibitor of the high-affinity, Na+-dependent plasma membrane glutamate transporter. cis-ACBD is a glutamate reuptake inhibitor. cis-ACBD also acts as linear competitive inhibitor of the uptake of D-[3H]aspartate[1][2].
Name cis-ACBD
CAS 73550-55-7
Formula C6H9NO4
Molar Mass 159.14
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Ai J, et al. Presynaptic excitability as a potential target for the treatment of the traumatic cerebellum. Pharmacology. 2004 Aug;71(4):192-8. [2]. Griffiths R, et al. L-trans-pyrrolidine-2,4-dicarboxylate and cis-1-aminocyclobutane-1,3-dicarboxylate behave as transportable, competitive inhibitors of the high-affinity glutamate transporters. Biochem Pharmacol. 1994 Jan 20;47(2):267-74.