| Bioactivity | cis-(Z)-Flupentixol dihydrochloride is a potent and selective DA D1/D2 receptor antagonist, with Ki values of 0.38 nM and 7 nM for D2 receptor and 5-HT2A, respectively[1][2]. |
| In Vivo | cis-(Z)-Flupentixol (0.25, or 0.5 mg/kg, i.p.) pretreatment dose-dependently reduces cocaine-induced activity[1]. Animal Model: |
| Name | cis-(Z)-Flupentixol dihydrochloride |
| CAS | 51529-01-2 |
| Formula | C23H27Cl2F3N2OS |
| Molar Mass | 507.44 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Jennifer M Wenzel, et al. The dopamine antagonist cis-flupenthixol blocks the expression of the conditioned positive but not the negative effects of cocaine in rats. Pharmacol Biochem Behav. 2013 Dec;114-115:90-6. [2]. Philip Seeman, et al. Atypical antipsychotics: mechanism of action. Can J Psychiatry. 2002 Feb;47(1):27-38. |
cis-(Z)-Flupentixol dihydrochloride
CAS: 51529-01-2 F: C23H27Cl2F3N2OS W: 507.44
cis-(Z)-Flupentixol dihydrochloride is a potent and selective DA D1/D2 receptor antagonist, with Ki values of 0.38 nM an
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