PeptideDB

cRGDfK-thioacetyl ester

CAS: 393781-65-2 F: C31H45N9O9S W: 719.81

cRGDfK-thioacetyl ester is a bioactive polypeptide molecule. It is composed of several amino acid residues, including cy
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Bioactivity cRGDfK-thioacetyl ester is a bioactive polypeptide molecule. It is composed of several amino acid residues, including cysteine (C), arginine (R), glycine (G), aspartic acid (D), phenylalanine (F), and lysine (K). This polypeptide has a specific sequence, called "cRGDfK". cRGDfK peptide has a selective affinity for integrins. cRGDfK peptide can modify NIR fluorescent probes for cancer targeting imaging[1][2].
Name cRGDfK-thioacetyl ester
CAS 393781-65-2
Sequence Cyclo(Arg-Gly-Asp-{d-Phe}-Lys)-{Ac-SCH2CO}
Shortening Cyclo(RGD-{d-Phe}-K)-{Ac-SCH2CO}
Formula C31H45N9O9S
Molar Mass 719.81
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Toti US, et al. Interfacial activity assisted surface functionalization: a novel approach to incorporate maleimide functional groups and cRGD peptide on polymeric nanoparticles for targeted drug delivery. Mol Pharm. 2010 Aug 2;7(4):1108-17. [2]. Gamage RS, et al. Comparison of cRGDfK Peptide Probes with Appended Shielded Heptamethine Cyanine Dye (s775z) for Near Infrared Fluorescence Imaging of Cancer. ACS Omega. 2021 Oct 30;6(44):30130-30139.