PeptideDB

cRGDfK-thioacetyl ester TFA

CAS: F: C31H45N9O9S.xC2HF3O2 W: 719.81 (free base)

cRGDfK-thioacetyl ester TFA is a bioactive polypeptide molecule. cRGDfK peptide has a selective affinity for integrins.
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity cRGDfK-thioacetyl ester TFA is a bioactive polypeptide molecule. cRGDfK peptide has a selective affinity for integrins. cRGDfK peptide can modify NIR fluorescent probes for cancer targeting imaging[1][2].
Name cRGDfK-thioacetyl ester TFA
Sequence Cyclo(Arg-Gly-Asp-{d-Phe}-Lys)-{Ac-SCH2CO}
Shortening Cyclo(RGD-{d-Phe}-K)-{Ac-SCH2CO}
Formula C31H45N9O9S.xC2HF3O2
Molar Mass 719.81 (free base)
Appearance 固体
Transport Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Reference [1]. Toti US, et al. Interfacial activity assisted surface functionalization: a novel approach to incorporate maleimide functional groups and cRGD peptide on polymeric nanoparticles for targeted drug delivery. Mol Pharm. 2010 Aug 2;7(4):1108-17. [2]. Gamage RS, et al. Comparison of cRGDfK Peptide Probes with Appended Shielded Heptamethine Cyanine Dye (s775z) for Near Infrared Fluorescence Imaging of Cancer. ACS Omega. 2021 Oct 30;6(44):30130-30139.