Bioactivity | cRGDfK-thioacetyl ester TFA is a bioactive polypeptide molecule. cRGDfK peptide has a selective affinity for integrins. cRGDfK peptide can modify NIR fluorescent probes for cancer targeting imaging[1][2]. | ||||||
Name | cRGDfK-thioacetyl ester TFA | ||||||
Sequence | Cyclo(Arg-Gly-Asp-{d-Phe}-Lys)-{Ac-SCH2CO} | ||||||
Shortening | Cyclo(RGD-{d-Phe}-K)-{Ac-SCH2CO} | ||||||
Formula | C31H45N9O9S.xC2HF3O2 | ||||||
Molar Mass | 719.81 (free base) | ||||||
Appearance | 固体 | ||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||
Storage | Sealed storage, away from moisture and light
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
||||||
Reference | [1]. Toti US, et al. Interfacial activity assisted surface functionalization: a novel approach to incorporate maleimide functional groups and cRGD peptide on polymeric nanoparticles for targeted drug delivery. Mol Pharm. 2010 Aug 2;7(4):1108-17. [2]. Gamage RS, et al. Comparison of cRGDfK Peptide Probes with Appended Shielded Heptamethine Cyanine Dye (s775z) for Near Infrared Fluorescence Imaging of Cancer. ACS Omega. 2021 Oct 30;6(44):30130-30139. |