Bioactivity | cGAS-IN-2 (compound 109) is a potent inhibitor of Cyclic GMP-AMP Synthase (cGAS), with IC50 of 0.01512 μM for h-cGAS[1]. |
CAS | 2765273-11-6 |
Formula | C16H18Cl2N2O2 |
Molar Mass | 341.23 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Ventus Therapeutics U.S., Inc. Pyrido[4,3-b]indole derivatives and their use as pharmaceuticals. World Intellectual Property Organization, WO2022066851 A1 2022-03-31 |