| Bioactivity | c-Met/HDAC-IN-3 (Compound 15f) is a dual c-Met and HDAC inhibitor with IC50 values of 12.50 nM and 26.97 nM against c-Met and HDAC1, respectively. c-Met/HDAC-IN-3 induces apoptosis and cause cell cycle arrest in G2/M phase[1]. |
| Invitro | c-Met/HDAC-IN-3 (Compound 15f) (0-20 μM, 72 h) shows antiproliferative activities against HCT-116, MCF-7 and A549 cells[1].c-Met/HDAC-IN-3 (0-5 μM, 48 h) induces apoptosis and arrests cell cycle at G2/M phase[1]. Cell Proliferation Assay[1] Cell Line: |
| Name | c-Met/HDAC-IN-3 |
| CAS | 2439175-23-0 |
| Formula | C34H35FN4O7 |
| Molar Mass | 630.66 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
c-Met/HDAC-IN-3
CAS: 2439175-23-0 F: C34H35FN4O7 W: 630.66
c-Met/HDAC-IN-3 (Compound 15f) is a dual c-Met and HDAC inhibitor with IC50 values of 12.50 nM and 26.97 nM against c-Me
Data collection：peptidedb@qq.com
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