Bioactivity | c-Met-IN-9, a 4-phenoxypyridine derivative, is a c-Met kinas inhibitor with an IC50 of 12 nM. c-Met-IN-9 induces cells apoptosis, and has antitumor activities[1]. |
Invitro | c-Met-IN-9 (Compound T14) shows remarkable antiproliferative activities against MKN-45, A549 and H460 cell lines with IC50 values of 0.64 μM, 1.92 μM and 2.68 μM, respectively[1]. c-Met-IN-9 could inhibit cells colony formation, induce cells apoptosis, and inhibit cells motility[1]. |
Name | c-Met-IN-9 |
CAS | 2760326-29-0 |
Formula | C25H19F2N5O3 |
Molar Mass | 475.45 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |