Bioactivity | c-Kit-IN-8 (Compound 53) is an inhibitor for c-Kit kinase, that inhibits uKIT kinase with an IC50 > 1 μM. c-Kit-IN-8 inhibits the proliferation of cancer cell GIST430 and BaF3 wildtype and mutants with IC50 > 0.1 μM[1]. |
CAS | 2941024-89-9 |
Formula | C24H26FN5O4 |
Molar Mass | 467.49 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Ahn YM, et al., Kit kinase inhibitors and methods of use thereof. US20240116877, |