Bioactivity | c-Fms-IN-10 is the derivative of thieno [3,2-d] pyrimidine, an kinase inhibitor of FMS (Colony stimulating factor-1 receptor, CSF-1R) with IC50 of 2 nM.c-Fms-IN-10 has anti-tumor activity[1]. | ||||||||||||
Name | c-Fms-IN-10 | ||||||||||||
CAS | 1527517-50-5 | ||||||||||||
Formula | C22H19N7OS | ||||||||||||
Molar Mass | 429.50 | ||||||||||||
Appearance | Solid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. Kim YY, et al. Synthesis and evaluation of thieno[3,2-d]pyrimidine derivatives as novel FMS inhibitors. Bioorg Med Chem Lett. 2019 Jan 15;29(2):271-275. |