| Bioactivity | c-ABL-IN-6 (compound A6) is a c-ABL inhibitor with IC50 value of 16.6 nM. c-ABL-IN-6 displays higher neuroprotective effects against SH-SY5Y cell death induced by MPP+ (HY-W008719). c-ABL-IN-6 can be used for the research of neurodegenerative disorder[1]. |
| Name | c-ABL-IN-6 |
| Formula | C27H21F3N6O2 |
| Molar Mass | 518.49 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Yang Z, et al. Discovery of conformationally constrained c-Abl inhibitors with potential neuroprotective effects against Parkinson's disease. Bioorg Med Chem. 2023 Dec 15;96:117532. |