| Bioactivity | c(avb6)-DOTA TFA is a conjugate of the αvβ6 integrin selective peptide ring modified with DPTA chelator. The Lu(III) complex of c(avb6)-DOTA TFA has a comparable affinity for αvβ6 integrin (IC50=0.8 nM) and can be used as a tumor diagnostic[1]. | ||||||
| Formula | C69H102F3N17O20 | ||||||
| Molar Mass | 1546.65 | ||||||
| Appearance | 固体 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
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| Reference | [1]. Färber S F, et al. Therapeutic radiopharmaceuticals targeting integrin αvβ6[J]. ACS omega, 2018, 3(2): 2428-2436. |