Bioactivity | anti-TNBC agent-3 (compound 3g) is an apoptosis inducer with anti-cancer cell proliferation activity. anti-TNBC agent-3 inhibits tumor growth and metastasis in triple-negative breast cancer (TNBC) xenograft models[1]. |
Invitro | anti-TNBC agent-3 (compound 3g) 抑制 K562 和 HepG2 增殖的 IC50 分别为 0.24 μM 和 0.25 μM[1]。 0 --> anti-TNBC agent-3 相关抗体: |
In Vivo | anti-TNBC agent-3 (compound 3g) (10 mg/kg, 20 mg/kg; ip) 抑制小鼠的三阴性乳腺癌 (TNBC) 异种移植模型中肿瘤的生长和转移[1]。 |
Name | anti-TNBC agent-3 |
CAS | 2422001-25-8 |
Formula | C29H39F2N7O |
Molar Mass | 539.66 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Zhang Q, et al. Synthesis and mechanism of action of new purine derivatives against triple negative breast cancer. Eur J Med Chem. 2023 Sep 7;261:115797.. . |