| Bioactivity | α-hydroxy Farnesyl phosphonic acid is a nonhydrolyzable analog of farnesyl pyrophosphate which acts as a competitive inhibitor of farnesyl transferase (FTase). At concentrations greater than 1 μM, α-hydroxy farnesyl phosphonic acid inhibits the processing of Ras in Ha-ras-transformed NIH3T3 cells. |
| CAS | 148796-53-6 |
| Formula | C15H27O4P |
| Molar Mass | 302.35 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Gibbs, et al. Selective inhibition of farnesyl-protein transferase blocks ras processing in vivo. J. Biol. Chem. 268(11), 7617-7620 (1993). |
alpha-Hydroxy farnesyl phosphonic acid
CAS: 148796-53-6 F: C15H27O4P W: 302.35
α-hydroxy Farnesyl phosphonic acid is a nonhydrolyzable analog of farnesyl pyrophosphate which acts as a competitive in
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