alpha-1,4-Galactosyltransferase (LgtC)

CAS: 52725-57-2 F: W:

CD77 synthase (A4GALT) is a glycosphingolipid-specific glycosyltransferase. CD77 synthase transfers a galactose to the a

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Bioactivity	CD77 synthase (A4GALT) is a glycosphingolipid-specific glycosyltransferase. CD77 synthase transfers a galactose to the alpha-1,4 position of lactosylceramide to form globotriaosylceramide. CD77 synthase can be used for the synthesis of P1 blood group antigens[1][2].
Name	alpha-1,4-Galactosyltransferase (LgtC)
CAS	52725-57-2
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Kaczmarek R, et al. Evaluation of an amino acid residue critical for the specificity and activity of human Gb3/CD77 synthase. Glycoconj J. 2016 Dec;33(6):963-973. [2]. Iwamura K, et al. The blood group P1 synthase gene is identical to the Gb3/CD77 synthase gene. A clue to the solution of the P1/P2/p puzzle. J Biol Chem. 2003 Nov 7;278(45):44429-38.