| Bioactivity | a-Helical Corticotropin Releasing Factor (12-41) is a 30 amino acids long, α-helical analogue of corticotropin releasing factor/hormone. Corticotropin releasing factor (CRF) is a hypothalamic hormone, which stimulates the secretion of adrenocorticotrophic hormone (ACTH). a-Helical Corticotropin Releasing Factor (12-41) would suppress the stimulatory effect[1][2]. |
| Invitro | a-Helical Corticotropin Releasing Factor (0.3 nM; 5-min pulses every 40 min alternately) shows the inhibitory effect on stimulated release of immunoreactive ACTH from perifused equine anterior pituitary cells in vitro.[2]. a-Helical Corticotropin Releasing Factor (0.5-5 μM) suppresses CRH-induced ACTH secretion[2]. |
| Name | a-Helical Corticotropin Releasing Factor (12-41) |
| CAS | 158535-55-8 |
| Shortening | FHLLREMLEMAKAEQEAEQAALNRLLLEEA-NH2 |
| Formula | C152H251N43O47S2 |
| Molar Mass | 3497.01 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
a-Helical Corticotropin Releasing Factor (12-41)
CAS: 158535-55-8 F: C152H251N43O47S2 W: 3497.01
a-Helical Corticotropin Releasing Factor (12-41) is a 30 amino acids long, α-helical analogue of corticotropin releasin
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