Zolimidine_product_DataBase

Bioactivity	Zolimidine, a derivate of imidazopyridine, is an orally active antiulcer agent. Zolimidine stimulates mucus secretion in intestinal mucosal cells and enhacnes intestinal wall more resistant to ulceration. Zolimidine exhibits gastroprotective effect in duodenal ulcer research[1][2].
In Vivo	Zolimidine (200 mg/kg；口服) 降低由 Indomethacin (HY-14397) (5 mg/kg/天，持续 8 天，直肠) 诱导的大鼠肠道溃疡的发生率[2]。Zolimidine (加在饮食中；1% 含量) 可降低豚鼠由角叉菜胶 (加在饮用水中；5% 含量，持续 40 天) 引起的肠溃疡的发生率[2]。
Name	Zolimidine
CAS	1222-57-7
Formula	C14H12N2O2S
Molar Mass	272.32
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Belohlavek D, et al. The effect of zolimidine, imidazopyridine-derivate, on the duodenal ulcer healing. Scand J Gastroenterol Suppl. 1979;54:44. [2]. Carminati GM, et al. Protective action of zolimidine against two different types of experimental intestinal ulcers. Farmaco, Edizione Pratica (1978), 33(2), 68-79.

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