Bioactivity | Zolantidine dimaleate (SKF 95282 dimaleate) is a potent, selective and cross the blood-brain barrier histamine H2 antagonist. Zolantidine dimaleate induces antinociception[1][2]. |
In Vivo | Zolantidine dimaleate (5、10、20、40 mg/kg;皮下注射) 在胆汁淤积大鼠中诱导抗伤害作用[2]。 Animal Model: |
Name | Zolantidine dimaleate |
CAS | 104076-39-3 |
Formula | C30H35N3O9S |
Molar Mass | 613.68 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Calcutt CR, et al. Zolantidine (SK&F 95282) is a potent selective brain-penetrating histamine H2-receptor antagonist. Br J Pharmacol. 1988 Jan;93(1):69-78. [2]. Hasanein P. Two histamine H2 receptor antagonists, zolantidine and cimetidine, modulate nociception in cholestatic rats. J Psychopharmacol. 2011 Feb;25(2):281-8. |