| Bioactivity | ZnAF-1F is a potent fluorophore for with an Kd value of 2.2 nM. ZnAF-1F can be used as fluorescent probes for Zn2+ in cells. ZnAF-1F shows λ excitation of 489 nm and λ emission of 514 nm[1][2][3]. |
| Invitro | ZnAF-1F (1 µM) shows an Kon value of 3.5*106 M-1s-1, and an Koff value of 7.7*10-3 s-1 in 100mM HEPES buffer[1].ZnAF-1F is a Zn sensors in neutral and slightly acidic conditions[2]. |
| Name | ZnAF-1F |
| CAS | 443302-08-7 |
| Formula | C34H26F2N4O5 |
| Molar Mass | 608.59 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Hirano T, et al. Improvement and biological applications of fluorescent probes for zinc, ZnAFs. J Am Chem Soc. 2002 Jun 12;124(23):6555-62. [2]. Zhaohua Dai, et al. Tailoring tripodal ligands for zinc sensing. New J. Chem., 2007,31, 1708-1718. [3]. Que EL, et al. Metals in neurobiology: probing their chemistry and biology with molecular imaging. Chem Rev. 2008 May;108(5):1517-49. |
ZnAF-1F
CAS: 443302-08-7 F: C34H26F2N4O5 W: 608.59
ZnAF-1F is a potent fluorophore for with an Kd value of 2.2 nM. ZnAF-1F can be used as fluorescent probes for Zn2+ in ce
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