PeptideDB

Zharp1-211

CAS: 2258671-41-7 F: C24H25N5O4 W: 447.49

Zharp1-211 is a potent inhibitor of RIPK1 kinase. Zharp1-211 significantly reduces the expression of JAK/STAT1-mediated
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity Zharp1-211 is a potent inhibitor of RIPK1 kinase. Zharp1-211 significantly reduces the expression of JAK/STAT1-mediated chemokines and MHC class II molecules in intestinal epithelial cells[1].
Name Zharp1-211
CAS 2258671-41-7
Formula C24H25N5O4
Molar Mass 447.49
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Yu X, et al. A novel RIPK1 inhibitor reduces GVHD in mice via a nonimmunosuppressive mechanism that restores intestinal homeostasis. Blood. 2023 Mar 2;141(9):1070-1086.