| Bioactivity | Zaurategrast ethyl ester sulfate (CDP323 sulfate), the ethyl ester prodrug of CT7758[1], is a α4β1/α4β7 integrin antagonist used for the treatment of inflammatory and autoimmune disorders[2]. |
| Target | α4β1/α4β7 integrin |
| Invitro | Zaurategrast ethyl ester sulfate (CDP323 sulfate), an ethyl ester prodrug of CT7758, shows some improvements in increasing mass transfer[1]. |
| Name | Zaurategrast ethyl ester sulfate |
| CAS | 1214261-78-5 |
| Formula | C28H29BrN4O3.1/2H2O4S |
| Molar Mass | 647.54 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Chanteux H, et al. Cross-Species Differences in the Preclinical Pharmacokinetics of CT7758, an α4β1/α4β7 Integrin Antagonist. Drug Metab Dispos. 2015 Sep;43(9):1381-91. [2]. Davenport RJ, et al. Alpha4-integrin antagonism--an effective approach for the treatment of inflammatory diseases? Drug Discov Today. 2007 Jul;12(13-14):569-76. |
Zaurategrast ethyl ester sulfate
CAS: 1214261-78-5 F: C28H29BrN4O3.1/2H2O4S W: 647.54
Zaurategrast ethyl ester sulfate (CDP323 sulfate), the ethyl ester prodrug of CT7758, is a α4β1/α4β7 integrin antago
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