| Bioactivity | Zankiren (A-72517) is an orally active inhibitor for renin. Zankiren exhibits renal vasodilator effect, through reduction of angiotensin II formation without affecting other vasodilator mechanisms[1]. |
| CAS | 138742-43-5 |
| Formula | C35H55N5O6S2 |
| Molar Mass | 705.97 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Wessale JL, Kleinert HD, Calzadilla SV, Kovar PJ, Rosenberg SH.Effects of renin inhibitor A-72517 on hemodynamics and cardiac function in sodium-depleted dogs.Am J Hypertens. 1993 Jun;6(6 Pt 1):514-21. [2]. Fisher ND, et al., Renal vascular responses to renin inhibition with zankiren in men. Clin Pharmacol Ther. 1995 Mar;57(3):342-8. |
Zankiren
CAS: 138742-43-5 F: C35H55N5O6S2 W: 705.97
Zankiren (A-72517) is an orally active inhibitor for renin. Zankiren exhibits renal vasodilator effect, through reductio
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