Bioactivity | Zaltidine dihydrochloride (CP-5736 dihydrochloride) is a highly specific H2 receptor antagonist with antisecretion activity. Zaltidine dihydrochloride reduces the stimulant effect of histamine on gastric acid secretion by binding to histamine H2 receptors on gastric parietal cells, thus reducing gastric acid production. Zaltidine dihydrochloride can be used in the study of gastric acid-related diseases such as duodenal ulcers[1]. |
CAS | 90274-23-0 |
Formula | C8H12Cl2N6S |
Molar Mass | 295.19 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Laferla G, et al. The antisecretory effects of zaltidine, a novel long‐acting H2‐receptor antagonist, in healthy volunteers and in subjects with a past history of duodenal ulcer[J]. British journal of clinical pharmacology, 1986, 22(4): 395-399. |