| Bioactivity | ZTA-261 is a highly selective and low toxic thyroid hormone receptor β subtype (THR-β) agonist (IC50=6.3 nM) that reduces body weight and visceral fat through a liothyronine (HY-A0070A) mediated pathway. ZTA-261 can be used in the study of lipid metabolism and obesity prevalence[1]. |
| Target | IC50：6.3 nM (THR-β) |
| CAS | 3049368-51-3 |
| Formula | C21H14F6O3 |
| Molar Mass | 428.32 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Nambo, et al. "Synthesis and preclinical testing of a selective beta-subtype agonist of thyroid hormone receptor ZTA-261." Communications Medicine 4.1 (2024): 152. |