| Bioactivity | ZSQ836 is an orally active dual covalent inhibitor of CDK12/CDK13, with an EC50 value of 32 nM against CDK12. ZSQ836 can induce apoptosis and exhibit anticancer activity in vivo. ZSQ836 can be used in the study of ovarian cancer[1]. |
| Target | EC50: 32 nM (CDK12). |
| CAS | 2634811-35-9 |
| Formula | C27H28AsClN6OS2 |
| Molar Mass | 627.06 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Cheng L, et al. Dual inhibition of CDK12/CDK13 targets both tumor and immune cells in ovarian cancer[J]. Cancer Research, 2022, 82(19): 3588-3602. |
ZSQ836
CAS: 2634811-35-9 F: C27H28AsClN6OS2 W: 627.06
ZSQ836 is an orally active dual covalent inhibitor of CDK12/CDK13, with an EC50 value of 32 nM against CDK12. ZSQ836 can
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