| Bioactivity | ZNU-IMB-Z15 (Compound Z15) is an antagonist and degrader of androgen receptor (AR). ZNU-IMB-Z15 can inhibit the proliferation of AR-positive castration-resistant prostate cancer (CRPC) cell lines and induce their apoptosis, exhibiting anticancer activity both in vivo and in vitro[1]. |
| CAS | 920915-26-0 |
| Formula | C20H17N3O3S2 |
| Molar Mass | 411.50 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Wu M, et al. Selective androgen receptor degrader (SARD) to overcome antiandrogen resistance in castration-resistant prostate cancer[J]. Elife, 2023, 12: e70700. |
ZNU-IMB-Z15
CAS: 920915-26-0 F: C20H17N3O3S2 W: 411.50
ZNU-IMB-Z15 (Compound Z15) is an antagonist and degrader of androgen receptor (AR). ZNU-IMB-Z15 can inhibit the prolifer
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