Bioactivity | ZNL-0056 is an orally active ATP-competitive inhibitor that targets both the Cys797 and Cys775 in the ATP binding site of EGFR. ZNL-0056 selectively inhibits EGFR and its downstream signaling in H3255 cells. ZNL-0056 can be used for the research of cancer[1]. |
In Vivo | 药代动力学分析[1]Route |
CAS | 2767987-38-0 |
Formula | C25H27N5O3S |
Molar Mass | 477.58 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Li Z, et al. Molecular Bidents with Two Electrophilic Warheads as a New Pharmacological Modality. ACS Central Science. 2024. |