| Bioactivity | ZJ-101 is a structurally simplified analog derived from the marine natural product superstolide A. ZJ-101 exhibits potent antiproliferative activity. ZJ-101 can target and inhibit O-glycosylation, thereby modulating the endomembrane system. ZJ-101 can inhibit cell-cell adhesion[1]. |
| Invitro | ZJ-101 对 MCF-7, MDA-MB-231, HCT-116 显示出抗增殖作用， IC50 分别为 40.8 nM (MCF-7), 61.1 nM (MDA-MB-231), 88.2 nM (HCT-116)[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> ZJ-101 相关抗体: |
| CAS | 1448446-23-8 |
| Formula | C30H43NO4 |
| Molar Mass | 481.67 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Qiu H, et al. Insights into the structure-activity relationship of the anticancer compound ZJ-101: A role played by the amide moiety. Bioorg Med Chem Lett. 2024 Jun 1;105:129741. |