| Bioactivity | ZINC13466751 is a potent inhibitor of HIF-1α/von Hippel-Lindau interaction with an IC50 of 2.0 µM[1]. |
| Target | IC50: 2.0 µM (HIF-1α/von Hippel-Lindau) |
| Name | ZINC13466751 |
| CAS | 117953-17-0 |
| Formula | C20H21N5O2 |
| Molar Mass | 363.41 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | -20°C, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen) |
| Reference | [1]. Xue X, et al. Discovery of novel inhibitors disrupting HIF-1α/von Hippel-Lindau interaction through shape-based screening and cascade docking. PeerJ. 2016 Dec 15;4:e2757. |